389. Analysis of Variable Factor in rCBF Measurement Using IMP-SPECT & Arterial Blood Sampling Method
نویسندگان
چکیده
منابع مشابه
Measurement of regional cerebral blood flow with 123I-IMP using one-point venous blood sampling and causality analysis: evaluation by comparison with conventional continuous arterial blood sampling.
OBJECTIVE Arterial input function represents the delivery of intravascular tracer to the brain. The optimal setting of this function is essential for measuring regional cerebral blood flow (rCBF) based on the microsphere model using N-isopropyl-4-[123I]iodoamphetamine (123I-IMP), in which the arterial 123I-IMP concentration (integral value) during the initial 5 min is usually applied. We develo...
متن کاملAssessment of regional cerebral blood flow (rCBF) in stroke using SPECT and N-isopropyl-(I-123)-p-iodoamphetamine (IMP).
In this study we assessed regional cerebral blood flow in patients with signs and symptoms of acute stroke using single-photon emission computed tomography (SPECT) and N-isopropyl I-123 p-iodoamphetamine (IMP). Twenty-five patients with acute cerebral infarction had both IMP brain perfusion studies and CT scans performed within one week of each other; 22 had positive and three had negative perf...
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متن کاملA simplified double-injection method to quantify cerebral blood flow and vascular reserve using iodine-123 IMP-SPECT.
UNLABELLED We developed and evaluated a simplified double-injection method for iodine-123 N-isopropyl-p-iodoamphetamine (IMP) to quantify regional cerebral blood flow (rCBF) twice in a single SPECT session. The method enabled rapid calculations of rCBF with five 10-minute SPECT scans, a fixed distribution volume (Vd), and one-point arterial blood sampling to calibrate a standard input function ...
متن کاملA comparative study of simple methods to measure regional cerebral blood flow using iodine-123-IMP SPECT.
UNLABELLED The aim of this study was to compare the accuracy and reliability of simple methods of quantifying regional cerebral blood flow (rCBF) with 123I-labeled N-isopropyl-p-iodoamphetamine (IMP) and SPECT and to determine which method was best. METHODS Four methods were examined: (a) the microsphere method with continuous withdrawal of arterial blood, which was based on a microsphere mod...
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ژورنال
عنوان ژورنال: Japanese Journal of Radiological Technology
سال: 1990
ISSN: 0369-4305,1881-4883
DOI: 10.6009/jjrt.kj00003322511